Premium
Systems‐Based Analysis of Modified tRNA Bases
Author(s) -
Globisch Daniel,
Pearson David,
Hienzsch Antje,
Brückl Tobias,
Wagner Mirko,
Thoma Ines,
Thumbs Peter,
Reiter Veronika,
Kneuttinger Andrea Christa,
Müller Markus,
Sieber Stephan A.,
Carell Thomas
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201103229
Subject(s) - phylogenetic tree , transfer rna , computational biology , computer science , biology , information retrieval , genetics , gene , rna
Quantification of modified tRNA nucleosides in 16 species reveals evolutionary development of modification levels corresponding to phylogenetic branching. Comparison of modification profiles additionally allows characterization of species and differentiation between a number of pathogenic and harmless bacterial strains.