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Improved Ruthenium‐Catalyzed Amination of Alcohols with Ammonia: Synthesis of Diamines and Amino Esters
Author(s) -
Imm Sebastian,
Bähn Sebastian,
Zhang Min,
Neubert Lorenz,
Neumann Helfried,
Klasovsky Florian,
Pfeffer Jan,
Haas Thomas,
Beller Matthias
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201103199
Subject(s) - amination , primary (astronomy) , ammonia , catalysis , ruthenium , chemistry , organic chemistry , atmosphere (unit) , reductive amination , combinatorial chemistry , physics , astronomy , thermodynamics
Diamination of diols : The first homogeneously catalyzed diaminations of primary and secondary diols with ammonia give the corresponding diamines. Other primary as well as secondary alcohols including hydroxy‐substituted esters can also be efficiently converted to primary amines. This atom‐efficient and selective amination method proceeds in an ammonia atmosphere without additional hydrogen sources.