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Inside Cover: Efficient and Stereodivergent Electrochemical Synthesis of Optically Pure Menthylamines (Angew. Chem. Int. Ed. 24/2011)
Author(s) -
Kulisch Jörn,
Nieger Martin,
Stecker Florian,
Fischer Andreas,
Waldvogel Siegfried R.
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201103180
Subject(s) - stereoselectivity , cathode , epimer , electrochemistry , cathodic protection , cationic polymerization , chemistry , int , cover (algebra) , combinatorial chemistry , stereochemistry , polymer chemistry , organic chemistry , catalysis , electrode , computer science , mechanical engineering , engineering , operating system
The choice of cathodic material determines which epimer of menthylamine is preferentially formed in a stereodivergent electroorganic synthesis. As S. R. Waldvogel and co‐workers report in their Communication on page 5564 ff., Hg cathodes provide selective access to (−)‐menthylamine, whereas a decorated Pb cathode directs the formation of (M+)‐neomenthylamine. A protective “glove” consisting of cationic additives controls the stereoselectivity, allows quantitative conversion, and avoids corrosion of the cathode.