Practical One‐Pot Preparation of Magnesium Di(hetero)aryl‐ and Magnesium Dialkenylboronates for Suzuki–Miyaura Cross‐Coupling Reactions | Zendy

Haag Benjamin A. | Zendy; Sämann Christoph | Zendy; Jana Anukul | Zendy; Knochel Paul | Zendy

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Practical One‐Pot Preparation of Magnesium Di(hetero)aryl‐ and Magnesium Dialkenylboronates for Suzuki–Miyaura Cross‐Coupling Reactions

Author(s) -

Haag Benjamin A.,

Sämann Christoph,

Jana Anukul,

Knochel Paul

Publication year - 2011

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.201103022

Subject(s) - aryl , magnesium , halide , chemistry , combinatorial chemistry , coupling reaction , atom (system on chip) , database , organic chemistry , catalysis , computer science , alkyl , embedded system

Mg for B : An atom‐economical one‐pot synthesis by direct magnesium insertion in the presence of B(OBu) 3 and LiCl allows a broad range of functionalized (hetero)aryl and alkenyl bromides to be converted into magnesium diorganoboronates 2 , which undergo Suzuki–Miyaura cross‐coupling reactions with various aryl (pseudo)halides (see scheme). Both aryl groups of 2 are transferred and furnish the products in good to excellent yields.

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