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Sequential SPECT and Optical Imaging of Experimental Models of Prostate Cancer with a Dual Modality Inhibitor of the Prostate‐Specific Membrane Antigen
Author(s) -
Banerjee Sangeeta Ray,
Pullambhatla Mrudula,
Byun Youngjoo,
Nimmagadda Sridhar,
Foss Catherine A.,
Green Gilbert,
Fox James J.,
Lupold Shawn E.,
Mease Ronnie C.,
Pomper Martin G.
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201102872
Subject(s) - prostate cancer , glutamate carboxypeptidase ii , prostate , dual (grammatical number) , modality (human–computer interaction) , computer science , cancer research , medicine , nuclear medicine , medical physics , chemistry , cancer , artificial intelligence , philosophy , linguistics
One reagent for two techniques : Compound [ 111 In] 1 provides a platform for sequential radionuclide and optical imaging of prostate cancer through targeting of the prostate‐specific membrane antigen. Because the same subject can be dual‐imaged after one injection of the agent, these findings support rapid clinical translation.