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Palladium‐Catalyzed Direct Synthesis of Organoboronic Acids
Author(s) -
Pilarski Lukasz T.,
Szabó Kálmán J.
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201102384
Subject(s) - palladium , reagent , aryl , boronic acid , catalysis , chemistry , boron , combinatorial chemistry , organic chemistry , alkyl
Diboronic acid in the spotlight : Molander et al. have developed an excellent method for the direct synthesis of aryl boronic acids from aryl chlorides (see scheme). In this palladium‐catalyzed procedure, diboronic acid, a notably underutilized reagent, was used as the boron source. The boronic acid products can be isolated from the procedure, or used in one‐pot reactions to give a wide range of boronates and biaryls.
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