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Highly Efficient Amide Synthesis from Alcohols and Amines by Virtue of a Water‐Soluble Gold/DNA Catalyst
Author(s) -
Wang Ye,
Zhu Dapeng,
Tang Lin,
Wang Sujing,
Wang Zhiyong
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201102374
Subject(s) - catalysis , substrate (aquarium) , amide , chemistry , scope (computer science) , combinatorial chemistry , organic chemistry , colloidal gold , nanotechnology , nanoparticle , computer science , materials science , biology , ecology , programming language
Gold takes to water : The synthesis of amides directly from alcohols and amines was realized by using a water‐soluble Au/DNA nanohybrid as the catalyst. The interactions between the gold nanoparticles, DNA, and water lead to high catalytic efficiency under mild reaction conditions. The wide substrate scope includes less‐basic aromatic amines, and this catalyst is recyclable.