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DNA‐Linked Nanoparticle Building Blocks for Programmable Matter
Author(s) -
Kim JinWoo,
Kim JeongHwan,
Deaton Russell
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201102342
Subject(s) - nanoparticle , computer science , nanotechnology , ligand (biochemistry) , template , dna , colloid , materials science , chemistry , biochemistry , receptor
One step at a time : DNA linkers were placed at defined locations and in defined 3D orientations on a colloidal nanoparticle. Because the implemented ligand‐replacement strategy was carried out sequentially, DNA linkers maximally segregated, producing a nanoparticle with linkers at 90 or 180° angles (see picture). These building blocks should enable assembly of anisotropic nanostructures with precisely designed geometry and complex functionality.

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