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Enhanced Nucleophilic Behavior of a Dimolybdenum Phosphinidene Complex: Multicomponent Reactions with Activated Alkenes and Alkynes in the Presence of CO or CNXyl
Author(s) -
Alvarez M. Angeles,
García M. Esther,
Ruiz Miguel A.,
Suárez Jaime
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201101940
Subject(s) - phosphinidene , regioselectivity , reactivity (psychology) , nucleophile , chemistry , ligand (biochemistry) , medicinal chemistry , combinatorial chemistry , organic chemistry , catalysis , medicine , biochemistry , alternative medicine , receptor , pathology
A ligand makes a difference : The reactivity of a dimolybdenum phosphinidene complex with alkenes and alkynes is substantially modified by the presence of two‐electron donors such as CO or CNXyl (Xyl=xylyl). Under these multicomponent reaction conditions, rapid formation of phosphametallacyclopentene rings takes place at room temperature. These reactions proceed in all cases with very high chemo‐ and regioselectivity.