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Total Synthesis of (−)‐Isatisine A
Author(s) -
Zhang Xiao,
Mu Tong,
Zhan Fuxu,
Ma Lijuan,
Liang Guangxin
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201101621
Subject(s) - indole test , computer science , intramolecular force , glycosylation , scheme (mathematics) , chemistry , information retrieval , world wide web , stereochemistry , mathematics , biochemistry , mathematical analysis
Short and sweet : (−)‐Isatisine A was constructed using common and inexpensive building blocks, such as indole and D ‐ribose (see scheme). The synthesis features an unprecedented intramolecular C glycosylation of an indole and an oxidative ring contraction.