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Gold for CC Coupling Reactions: A Swiss‐Army‐Knife Catalyst?
Author(s) -
Wegner Hermann A.,
Auzias Mathieu
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201101603
Subject(s) - catalysis , coupling reaction , redox , lewis acids and bases , nanotechnology , combinatorial chemistry , transition metal , chemistry , coupling (piping) , metal , materials science , organic chemistry , metallurgy
For organic chemists, the construction of CC bonds is the most essential aspect of the assembly of molecules. Transition‐metal‐catalyzed coupling reactions have evolved as one of the key tools for this task. Lately, gold has also emerged as a catalyst for this kind of transformation. Gold, with its special properties as a mild carbophilic π Lewis acid, its ability to insert into CH bonds, and, as discovered recently, its ability to undergo redox transformations, offers the opportunity to apply all this potent proficiency for the construction of compounds in an efficient and economical way. This Minireview critically presents the CC coupling reactions enabled by gold catalysts to encourage further research activities in this promising area of oxidation/reduction gold catalysts.