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Facile Preparation of Multifunctional Upconversion Nanoprobes for Multimodal Imaging and Dual‐Targeted Photothermal Therapy
Author(s) -
Cheng Liang,
Yang Kai,
Li Yonggang,
Chen Jianhua,
Wang Chao,
Shao Mingwang,
Lee ShuitTong,
Liu Zhuang
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201101447
Subject(s) - photothermal therapy , photon upconversion , materials science , nanoparticle , nanotechnology , magnetic resonance imaging , iron oxide nanoparticles , absorption (acoustics) , luminescence , optoelectronics , medicine , composite material , radiology
Jack of all trades : A multifunctional nanoparticle (MFNP) integrates an upconversion nanoparticle (see picture, green), a layer of iron oxide nanoparticles (black), and a gold shell (red). The system can be used for in vitro targeted upconversion luminescence, magnetic resonance, and light scattering multimodal imaging of cells. The near‐infrared optical absorption of MFNPs also enables photothermal destruction of cancer cells.