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Photocontrol of Contracting Muscle Fibers
Author(s) -
Hoppmann Christian,
Schmieder Peter,
Domaing Petra,
Vogelreiter Gabriela,
Eichhorst Jenny,
Wiesner Burkhard,
Morano Ingo,
RückBraun Karola,
Beyermann Michael
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201101398
Subject(s) - nitric oxide , skeletal muscle , chemistry , nitric oxide synthase , biophysics , microbiology and biotechnology , peptide , ligand (biochemistry) , biochemistry , receptor , anatomy , biology , organic chemistry
A twitch in time : Light‐directed inhibition of the interaction between α‐1‐syntrophin and neuronal NO synthase (nNOS) in living skeletal muscle with a cell‐permeable photoswitchable nNOS‐derived peptide ligand results in photocontrol of muscle performance and nitric oxide signaling.