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Patchy, Anisotropic Microspheres with Soft Protein Islets
Author(s) -
Kamalasanan Kaladhar,
Jhunjhunwala Siddharth,
Wu Jiamin,
Swanson Alexandra,
Gao Di,
Little Steven R.
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201101217
Subject(s) - microsphere , condensation , computer science , anisotropy , nanotechnology , chemistry , materials science , physics , optics , chemical engineering , engineering , thermodynamics
Useful contacts : A new method to achieve regular patterns generates anisotropic, “patchy” microspheres by using interfacial condensation of a liquid mask and the proximity of the particles to their neighbors to determine a mask pattern. The microspheres are separated from the scaffold and labeled with a first protein at non‐mask regions (green) followed by removal of the mask and immobilization of a second protein (red).