Premium
Total Synthesis of (−)‐Conophylline and (−)‐Conophyllidine
Author(s) -
Hanya Yuki,
Tokuyama Hidetoshi,
Fukuyama Tohru
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201100981
Subject(s) - ring (chemistry) , total synthesis , aspidosperma , stereochemistry , mathematics , chemistry , combinatorics , organic chemistry , indole test
Double take : The total syntheses of the title compounds were accomplished in a highly convergent manner. The approach features the regio‐ and diastereoselective Polonovski–Potier‐type reaction for the coupling of two aspidosperma skeletons and the formation of the dihydrofuran ring. Troc=2,2,2‐trichloroethoxycarbonyl.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom