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Surface Functionalization by Strain‐Promoted Alkyne–Azide Click Reactions
Author(s) -
Manova Radostina,
van Beek Teris A.,
Zuilhof Han
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201100835
Subject(s) - surface modification , azide , alkyne , biomolecule , click chemistry , catalysis , nanotechnology , combinatorial chemistry , chemistry , materials science , organic chemistry
Clicks without Cu : There is a growing demand for reproducible site‐specific functionalization of surfaces with biomolecules without introduction of unwanted groups or catalysts, as they may interfere with later applications. The title reactions (see picture) could fulfill these requirements, and four recent applications are discussed.
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