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Biosensing Platform Based on Fluorescence Resonance Energy Transfer from Upconverting Nanocrystals to Graphene Oxide
Author(s) -
Zhang Cuiling,
Yuan Yunxia,
Zhang Shiming,
Wang Yuhui,
Liu Zhihong
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201100769
Subject(s) - graphene , förster resonance energy transfer , fluorescence , oxide , nanocrystal , biosensor , concanavalin a , phosphor , nanotechnology , energy transfer , materials science , resonant inductive coupling , chemistry , optoelectronics , biochemistry , optics , chemical physics , organic chemistry , physics , in vitro
A glucose sensor based on FRET between concanavalin A (ConA)‐labeled upconverting phosphor (UCP) nanocrystals and chitosan (CS)‐labeled graphene oxide (GO) is presented. Binding of ConA to CS quenches the fluorescence of UCP, which is restored in the presence of glucose, owing to competition between glucose and CS for ConA (see picture).