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Gold‐Catalyzed Hydroamination of Alkynes and Allenes with Parent Hydrazine
Author(s) -
Kinjo Rei,
Donnadieu Bruno,
Bertrand Guy
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201100740
Subject(s) - hydroamination , hydrazine (antidepressant) , cationic polymerization , chemistry , catalysis , ligand (biochemistry) , carbene , alkyl , organic chemistry , medicinal chemistry , combinatorial chemistry , biochemistry , receptor , chromatography
A diverse array of nitrogen‐containing compounds were formed by the addition of hydrazine to alkynes, diynes, enynes, and allenes in the presence of cationic gold(I) complexes with a cyclic (alkyl)(amino)carbene ligand (see scheme; the X‐ray crystal structure of the gold–hydrazine complex is shown). This hydroamination is an ideal initial step for the preparation of acyclic and heterocyclic bulk chemicals. Dipp=2,6‐diisopropylphenyl.