Allyl‐, Allenyl‐, and Propargyl‐Transfer Reactions through Cleavage of CC Bonds Catalyzed by an N‐Heterocyclic Carbene/Copper Complex: Synthesis of Multisubstituted Pyrroles | Zendy

Sai Masahiro | Zendy; Yorimitsu Hideki | Zendy; Oshima Koichiro | Zendy

Premium

Allyl‐, Allenyl‐, and Propargyl‐Transfer Reactions through Cleavage of CC Bonds Catalyzed by an N‐Heterocyclic Carbene/Copper Complex: Synthesis of Multisubstituted Pyrroles

Author(s) -

Sai Masahiro,

Yorimitsu Hideki,

Oshima Koichiro

Publication year - 2011

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.201100631

Subject(s) - propargyl , carbene , regioselectivity , catalysis , chemistry , copper , cleavage (geology) , bond cleavage , medicinal chemistry , combinatorial chemistry , organic chemistry , materials science , fracture (geology) , composite material

Cat. in the bag : The pictured copper complex can promote CC bond cleavage through retro‐allylation of homoallyl alcohols to form allylcopper species. This process is applicable to catalytic allylation of aldehydes and imines with homoallyl alcohols. The method has also been extended to regioselective allenylation and propargylation of imines.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research