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Palladium‐Catalyzed Ring‐Contraction and Ring‐Expansion Reactions of Cyclic Allyl Amines
Author(s) -
Dubovyk Igor,
Pichugin Dmitry,
Yudin Andrei K.
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201100612
Subject(s) - palladium , amination , ring (chemistry) , allylic rearrangement , nucleophile , chemistry , catalysis , cyclic amines , contraction (grammar) , medicinal chemistry , organic chemistry , biology , endocrinology
Ring around the rosy : An amino group can act as the leaving group or the nucleophile in a palladium‐catalyzed allylic amination. As a result, readily accessible cyclic amines can be either ring contracted or ring expanded (see scheme).

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