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Simple Synthesis and Functionalization of Iron Nanoparticles for Magnetic Resonance Imaging
Author(s) -
Cheong Soshan,
Ferguson Peter,
Feindel Kirk W.,
Hermans Ian F.,
Callaghan Paul T.,
Meyer Claire,
Slocombe Angela,
Su ChiaHao,
Cheng FongYu,
Yeh ChenSheng,
Ingham Bridget,
Toney Michael F.,
Tilley Richard D.
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201100562
Subject(s) - nanoparticle , surface modification , nanotechnology , magnetic resonance imaging , magnetic nanoparticles , iron oxide , computer science , core (optical fiber) , iron oxide nanoparticles , simple (philosophy) , shell (structure) , materials science , chemistry , medicine , radiology , organic chemistry , philosophy , telecommunications , epistemology , composite material
Visualizing small tumors : A novel, facile synthesis leads to the formation of strongly magnetic single‐crystal core/shell iron/iron oxide nanoparticles without the use of highly toxic chemicals. The core/shell nanoparticles are highly effective MRI contrast agents and enable unambiguous detection of small tumors of 1–3 mm in vivo (see picture).