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Gold‐Nanoshelled Microcapsules: A Theranostic Agent for Ultrasound Contrast Imaging and Photothermal Therapy
Author(s) -
Ke Hengte,
Wang Jinrui,
Dai Zhifei,
Jin Yushen,
Qu Enze,
Xing Zhanwen,
Guo Caixin,
Yue Xiuli,
Liu Jibin
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201008286
Subject(s) - biocompatibility , photothermal therapy , materials science , nanotechnology , biomedical engineering , microbubbles , cancer therapy , ultrasound , colloidal gold , nanoshell , ultrasound imaging , nanoparticle , cancer , medicine , radiology , metallurgy
A valuable shell : The combination of electrostatic deposition of gold nanoparticles onto microcapsules and a surface seeding method results in the formation of gold nanoshells (see picture). This nano/microcomposite is able to operate as a theranostic agent for both contrast‐enhanced ultrasonic imaging (diagnostic) and photohyperthermia (therapeutic), and thus holds a great potential for photothermal therapy in cancer treatment.