Formal Asymmetric Synthesis of Echinopine A and B | Zendy

Peixoto Philippe A. | Zendy; Severin Rene | Zendy; Tseng ChihChung | Zendy; Chen David Y.K. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Formal Asymmetric Synthesis of Echinopine A and B

Author(s) -

Peixoto Philippe A.,

Severin Rene,

Tseng ChihChung,

Chen David Y.K.

Publication year - 2011

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.201008000

Subject(s) - intramolecular force , cycloisomerization , computer science , stereochemistry , enyne , chemistry , combinatorial chemistry , organic chemistry , catalysis

Enticing structures : The formal syntheses of 1 and 2 were accomplished by using a cascade strategy involving an enyne cycloisomerization reaction and an intramolecular Diels–Alder reaction starting from 3 . The resulting 4 underwent a late‐stage ring contraction to enable the preparation of a reported advanced intermediate, thereby constituting a formal synthesis of the structurally intriguing title compounds.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research