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Synchronized Inductive Desorption Electrospray Ionization Mass Spectrometry
Author(s) -
Huang Guangming,
Li Guangtao,
Ducan Jason,
Ouyang Zheng,
Cooks R. Graham
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201007819
Subject(s) - mass spectrometry , desorption electrospray ionization , desorption , electrospray ionization , ionization , extractive electrospray ionization , analytical chemistry (journal) , ambient ionization , mass spectrum , electrospray , chemistry , ion , chromatography , computer science , sample preparation in mass spectrometry , thermal ionization mass spectrometry , chemical ionization , organic chemistry , adsorption
Well‐orchestrated : A new mass spectrometry protocol (see picture) synchronizes microdroplet creation, nebulizing gas pulsing, and DAPI interface opening. A number of advances result: 100‐fold improved detection limit, simultaneous positive and negative ion spectra, and decreased spray volumes in desorption electrospray ionization (DESI).

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