Premium
Automatic Molecular Weaving Prototyped by Using Single‐Stranded DNA
Author(s) -
Ciengshin Tanashaya,
Sha Ruojie,
Seeman Nadrian C.
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201007685
Subject(s) - weaving , dna , engineering drawing , nucleotide , computer science , toroid , information retrieval , computational biology , engineering , biology , genetics , mechanical engineering , gene , physics , plasma , quantum mechanics
DNA weaves a braided pattern : Two DNA single strands with mixed D ‐ and L ‐ nucleotides combine to weave a braided toroidal link. 5′,5′ linkages (fused circles) and 3′,3′ linkages (bow‐tie structures) are needed to maintain the strand polarity. Properly placed L ‐nucleotides are needed to achieve the woven pattern.