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Site‐Specific Synthesis and In Situ Immobilization of Fluorescent Silver Nanoclusters on DNA Nanoscaffolds by Use of the Tollens Reaction
Author(s) -
Pal Suchetan,
Varghese Reji,
Deng Zhengtao,
Zhao Zhao,
Kumar Ashok,
Yan Hao,
Liu Yan
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201007529
Subject(s) - nanoclusters , fluorescence , dna , covalent bond , sugar , combinatorial chemistry , nanotechnology , in situ , chemistry , reagent , materials science , computational biology , computer science , biochemistry , biology , organic chemistry , optics , physics
Origami embellished with silver : DNA strands with specific sequences and covalently attached sugar moieties were used for the site‐specific incorporation of the sugar units on a DNA origami scaffold. This approach enabled the subsequent site‐specific synthesis and in situ immobilization of fluorescent Ag clusters at predefined positions on the DNA nanoscaffold by treatment with the Tollens reagent (see picture).