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Inside Cover: Microfluidic Multicolor Encoding of Microspheres with Nanoscopic Surface Complexity for Multiplex Immunoassays (Angew. Chem. Int. Ed. 5/2011)
Author(s) -
Kim ShinHyun,
Shim Jae Won,
Yang SeungMan
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201007478
Subject(s) - microsphere , microfluidics , nanotechnology , multiplex , materials science , nanoscopic scale , biomolecule , controllability , chemical engineering , bioinformatics , mathematics , engineering , biology
Transparent microspheres can be optically encoded with color core droplets, as shown by S.‐H. Kim, J. W. Shim, and S.‐M. Yang in their Communication on page 1171 ff. A microfluidic device produces and manipulates double‐emulsion droplets containing the desired number of color core droplets with unprecedented controllability. The droplets are then photopolymerized to produce microspheres. Silica particle arrays on the surface of the encoded microspheres enable biomolecules to be immobilized.