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Laser‐Induced Cell Detachment and Patterning with Photodegradable Polymer Substrates
Author(s) -
Pasparakis George,
Manouras Theodore,
Selimis Alexandros,
Vamvakaki Maria,
Argitis Panagiotis
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201007310
Subject(s) - polymer , photodissociation , excimer laser , laser , acetal , materials science , polymer science , degradation (telecommunications) , nanotechnology , chemistry , photochemistry , computer science , optics , stereochemistry , physics , telecommunications , composite material
A glimpse of light is all it takes : Polymers that undergo main‐chain scission at remarkably low photolysis energies were developed as efficient photodegradable substrates for safe laser‐mediated cell detachment and patterning. The polymers, which contain acetal or ketal units in their backbone along with suitable absorbing groups, underwent fast degradation to release live cells upon irradiation with an excimer laser (see picture).