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Oxidizing Directing Groups Enable Efficient and Innovative CH Activation Reactions
Author(s) -
Patureau Frederic W.,
Glorius Frank
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201007241
Subject(s) - oxidizing agent , reactivity (psychology) , covalent bond , catalysis , chemistry , selectivity , coupling reaction , metal , combinatorial chemistry , coupling (piping) , photochemistry , organic chemistry , materials science , metallurgy , medicine , alternative medicine , pathology
Come in! The use of internal oxidants, embedded in the directing group, in CH activation reactions can lead to higher levels of selectivity and reactivity under milder conditions (see examples). An internal oxidant can be defined as a covalent bond within one of the coupling substrates which oxidizes the metal catalyst. This should open up new avenues in the field of CH activation.