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Dynamic and Programmable DNA‐Templated Boronic Ester Formation
Author(s) -
Martin Anthony R.,
Barvik Ivan,
Luvino Delphine,
Smietana Michael,
Vasseur JeanJacques
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201007170
Subject(s) - physics , art history , art
Plug and play : A helix with a boronate ester linkage was constructed by DNA‐ or RNA‐templated assembly through the plugging together of appropriately designed half‐sequences, one with a boronic acid at its 5′ end, the other with a ribonucleotide at its 3′ end. The two hybridization steps in the three‐component assembly (see picture) could be controlled reversibly by external stimuli, including an acid or base, cyanide ions, or fructose.