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Highly Enantioselective Catalytic Benzoyloxylation of 3‐Aryloxindoles Using Chiral VAPOL Calcium Phosphate
Author(s) -
Zhang Zuhui,
Zheng Wenhua,
Antilla Jon C.
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201006595
Subject(s) - enantioselective synthesis , oxindole , catalysis , chemistry , calcium , phosphate , salt (chemistry) , combinatorial chemistry , transformation (genetics) , organic chemistry , biochemistry , gene
Keeping straight : The highly enantioselective title reaction provides novel and straightforward access to 3‐hydroxy‐2‐oxindole derivatives (see scheme). This transformation signifies the first example of a chiral phosphate calcium salt activating a benzoyl peroxide.