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Iridium‐Mediated Borylation of Benzylic CH Bonds by Borohydride
Author(s) -
Tang Christina Y.,
Smith William,
Thompson Amber L.,
Vidovic Dragoslav,
Aldridge Simon
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201006320
Subject(s) - iridium , borylation , intramolecular force , chemistry , borohydride , simple (philosophy) , combinatorial chemistry , computer science , medicinal chemistry , stereochemistry , catalysis , organic chemistry , philosophy , alkyl , epistemology , aryl
Simple source : An intramolecular iridium‐mediated CH borylation proceeds through transfer of a BH 3 fragment from borohydride to a benzylic carbon center (see scheme; coe=cyclooctene). Simple and inexpensive LiBH 4 is thus utilized as the boron source in CH to CB conversion.