Premium
Iridium‐Mediated Borylation of Benzylic CH Bonds by Borohydride
Author(s) -
Tang Christina Y.,
Smith William,
Thompson Amber L.,
Vidovic Dragoslav,
Aldridge Simon
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201006320
Subject(s) - iridium , borylation , intramolecular force , chemistry , borohydride , simple (philosophy) , combinatorial chemistry , computer science , medicinal chemistry , stereochemistry , catalysis , organic chemistry , philosophy , alkyl , epistemology , aryl
Simple source : An intramolecular iridium‐mediated CH borylation proceeds through transfer of a BH 3 fragment from borohydride to a benzylic carbon center (see scheme; coe=cyclooctene). Simple and inexpensive LiBH 4 is thus utilized as the boron source in CH to CB conversion.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom