Palladium(II)‐Catalyzed CH Bond Arylation of Electron‐Deficient Arenes at Room Temperature | Zendy

Tredwell Matthew J. | Zendy; Gulias Moises | Zendy; Gaunt Bremeyer Nadine | Zendy; Johansson Carin C. C. | Zendy; Collins Beatrice S. L. | Zendy; Gaunt Matthew J. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Palladium(II)‐Catalyzed CH Bond Arylation of Electron‐Deficient Arenes at Room Temperature

Author(s) -

Tredwell Matthew J.,

Gulias Moises,

Gaunt Bremeyer Nadine,

Johansson Carin C. C.,

Collins Beatrice S. L.,

Gaunt Matthew J.

Publication year - 2011

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.201005990

Subject(s) - palladium , imine , catalysis , aryl , chemistry , medicinal chemistry , combinatorial chemistry , polymer chemistry , organic chemistry , alkyl

Mild and tolerant : A novel Pd II ‐catalyzed CH bond arylation with aryl‐BF 3 K salts transforms various electron‐deficient arenes under mild reaction conditions. Benzaldehydes are functionalized in the ortho position using a temporary imine directing group that controls the cyclopalladation. A broad range of benzaldimines are compatible with this process (see scheme).

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research