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Remote Supramolecular Control of Catalyst Selectivity in the Hydroformylation of Alkenes
Author(s) -
Dydio Paweł,
Dzik Wojciech I.,
Lutz Martin,
de Bruin Bas,
Reek Joost N. H.
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201005173
Subject(s) - hydroformylation , regioselectivity , selectivity , phosphine , supramolecular chemistry , catalysis , chemistry , computer science , combinatorial chemistry , organic chemistry , molecule , rhodium
In the pocket : The supramolecular interactions between a Rh phosphine catalyst equipped with an anion‐binding pocket and alkenes that contain anionic functionalities (see picture) provide an excellent design concept to achieve remote control of the regioselectivity in hydroformylation reactions. The 4‐pentenoate and 3‐butenylphosphonate, which fit tightly between the Rh center and the pocket, were hydroformylated with unprecedented selectivity.