Facile DNA Immobilization on Surfaces through a Catecholamine Polymer | Zendy

Ham Hyun Ok | Zendy; Liu Zhongqiang | Zendy; Lau K. H. Aaron | Zendy; Lee Haeshin | Zendy; Messersmith Phillip B. | Zendy

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Facile DNA Immobilization on Surfaces through a Catecholamine Polymer

Author(s) -

Ham Hyun Ok,

Liu Zhongqiang,

Lau K. H. Aaron,

Lee Haeshin,

Messersmith Phillip B.

Publication year - 2011

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.201005001

Subject(s) - polymer , nanotechnology , fabrication , substrate (aquarium) , materials science , dna , chemistry , computer science , biology , biochemistry , composite material , medicine , ecology , alternative medicine , pathology

Simple immersion of noble metals, oxides, semiconductors, and synthetic polymer substrates in a mussel‐mimetic catecholamine polymer solution p(DOMA‐AEMA) leads to formation of a thin film on the substrate. The resulting coated substrates can bind DNA without further surface treatment. This approach provides a new entrance to DNA microarray fabrication.

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