A Chiral‐Anion Generator: Application to Catalytic Desilylative Kinetic Resolution of Silyl‐Protected Secondary Alcohols | Zendy

Yan Hailong | Zendy; Jang Hyeong Bin | Zendy; Lee JiWoong | Zendy; Kim Hong Ki | Zendy; Lee Soon Won | Zendy; Yang Jung Woon | Zendy; Song Choong Eui | Zendy

Premium

A Chiral‐Anion Generator: Application to Catalytic Desilylative Kinetic Resolution of Silyl‐Protected Secondary Alcohols

Author(s) -

Yan Hailong,

Jang Hyeong Bin,

Lee JiWoong,

Kim Hong Ki,

Lee Soon Won,

Yang Jung Woon,

Song Choong Eui

Publication year - 2010

Publication title -

angewandte chemie international edition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 1433-7851

DOI - 10.1002/anie.201004777

Subject(s) - silylation , kinetic resolution , enantioselective synthesis , halogen , fluoride , kinetic energy , chemistry , catalysis , generator (circuit theory) , ion , combinatorial chemistry , organic chemistry , physics , inorganic chemistry , thermodynamics , power (physics) , alkyl , quantum mechanics

Getting the grips on fluoride : Chiral hydroxy‐terminated polyethers bearing a 3,3′‐halogen‐substituted chiral 1,1′‐bi‐2‐naphthol (BINOL) unit manifest a new structural motif for chiral‐anion generators. Their unique properties are revealed through highly enantioselective desilylative kinetic resolution of a variety of silyl‐protected racemic alcohols with KF (see scheme).

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research