z-logo
Premium
Regioselective Nickel‐Catalyzed Reductive Couplings of Enones and Allenes
Author(s) -
Li Wei,
Chen Nan,
Montgomery John
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201004740
Subject(s) - regioselectivity , alkene , conjugate , chemistry , catalysis , complement (music) , combinatorial chemistry , nickel , coupling (piping) , reductive elimination , organic chemistry , materials science , mathematics , mathematical analysis , biochemistry , complementation , metallurgy , gene , phenotype
Alkenes made easy : In a complement to coupling processes of terminal alkynes, the reductive coupling of enones and allenes provides access to conjugate addition products that possess a 1,1‐disubstituted alkene (see scheme; cod=1,5‐cyclooctadiene). The solvent composition and reducing agent must be carefully matched to allow high levels of regioselectivity to be observed.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here