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Enantioselective Hydrogenation with Chiral Frustrated Lewis Pairs
Author(s) -
Chen Dianjun,
Wang Yutian,
Klankermayer Jürgen
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201004525
Subject(s) - enantioselective synthesis , frustrated lewis pair , frustration , lewis acids and bases , chemistry , materials science , catalysis , organic chemistry , physics , condensed matter physics
No subsequent frustration : Frustrated Lewis pairs (FLPs) have been recently introduced as an unprecedented possibility to activate hydrogen. On the basis of this concept the first example of highly enantioselective catalytic hydrogenation of imines using chiral FLPs has been demonstrated (see scheme).