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4‐Substituted tert ‐Butyl Phenylazocarboxylates—Synthetic Equivalents for the para ‐Phenyl Radical Cation
Author(s) -
Höfling Sarah B.,
Bartuschat Amelie L.,
Heinrich Markus R.
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201004508
Subject(s) - electrophile , radical , chemistry , nucleophile , radical ion , aryl , medicinal chemistry , aryl radical , equivalent , organic chemistry , ion , catalysis , biochemistry , alkyl
First electrophile, then radical : 4‐Substituted tert ‐butyl phenylazocarboxylates 1 are versatile synthetic equivalents of the para ‐phenyl radical cation 2 . The tert ‐butyloxycarbonylazo group enables nucleophilic substitutions to proceed under mild conditions and can later be employed for the generation of aryl radicals.