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Cover Picture: Palladium‐Catalyzed Coupling of Aldehyde‐Derived Hydrazones: Practical Synthesis of Triazolopyridines and Related Heterocycles (Angew. Chem. Int. Ed. 45/2010)
Author(s) -
Thiel Oliver R.,
Achmatowicz Michal M.,
Reichelt Andreas,
Larsen Robert D.
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201004361
Subject(s) - palladium , chemistry , aldehyde , catalysis , cover (algebra) , bicyclic molecule , combinatorial chemistry , organic chemistry , int , computer science , mechanical engineering , engineering , operating system
Pharmaceutically active compounds … … and their intermediates require selective, efficient, and robust syntheses that utilize green chemistry principles. In their Communication on page 8395 ff., O. R. Thiel, M. Achmatowicz, and co‐workers describe a two‐step procedure involving selective palladium‐catalyzed carbon–nitrogen bond formation followed by a clean oxidative cyclization that affords access to a variety of bicyclic and tricyclic heteroaromatic scaffolds.