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Enantioselective Cobalt‐Catalyzed Preparation of Trifluoromethyl‐Substituted Cyclopropanes
Author(s) -
Morandi Bill,
Mariampillai Brian,
Carreira Erick M.
Publication year - 2011
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201004269
Subject(s) - enantioselective synthesis , cobalt , trifluoromethyl , catalysis , chemistry , combinatorial chemistry , scheme (mathematics) , computer science , organic chemistry , mathematics , alkyl , mathematical analysis
Easy access on water : A cobalt‐catalyzed asymmetric preparation of trifluoromethylcyclopropanes has been developed that yields high enantioselectivities with a broad range of styrene substrates (see scheme). The reaction presents a new access to enantioenriched CF 3 ‐containing building blocks.
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