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Asymmetric Cyclopropanation of Alkenes with Dimethyl Diazomalonate Catalyzed by Chiral Diene–Rhodium Complexes
Author(s) -
Nishimura Takahiro,
Maeda Yuko,
Hayashi Tamio
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201003775
Subject(s) - cyclopropanation , cyclopropane , rhodium , diene , chemistry , intermolecular force , ligand (biochemistry) , enantioselective synthesis , stereochemistry , organic chemistry , catalysis , molecule , ring (chemistry) , biochemistry , natural rubber , receptor
Chiral tridentate ligand : A chiral diene–rhodium complex ( 1 ; see scheme) was found to catalyze the intermolecular asymmetric cyclopropanation of alkenes with dimethyl diazomalonate to give 1,1‐cyclopropane diesters in good yields and with high enantioselectivity.