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A Polymer‐Supported Chiral Dirhodium(II) Complex: Highly Durable and Recyclable Catalyst for Asymmetric Intramolecular CH Insertion Reactions
Author(s) -
Takeda Koji,
Oohara Tadashi,
Anada Masahiro,
Nambu Hisanori,
Hashimoto Shunichi
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201003730
Subject(s) - intramolecular force , copolymer , styrene , monomer , catalysis , chemistry , linker , combinatorial chemistry , polymer , polymer chemistry , computer science , organic chemistry , operating system
A highly effective immobilization of [Rh 2 ( S ‐PTTL) 4 ] (PTTL =N ‐phthaloyl‐ tert ‐leucinate) has been achieved by copolymerization of monomer 1 with styrene and a flexible cross‐linker. The immobilized catalyst promoted the title reaction at −78 °C with high enantioselectivity, and could be used for up to 100 cycles with a low level of leaching (0.28 ppm).