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An Intermolecular Palladium‐Catalyzed Diamination of Unactivated Alkenes
Author(s) -
Iglesias Álvaro,
Pérez Edwin G.,
Muñiz Kilian
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201003653
Subject(s) - hypervalent molecule , palladium , intermolecular force , catalysis , reagent , chemistry , combinatorial chemistry , amination , organic chemistry , molecule
Adding 2Ns : Palladium catalysis introduces two nitrogen groups in a new regio and chemoselective diamination of non‐activated alkenes that proceeds under entirely intermolecular reaction control. This palladium‐catalyzed reaction employs commercial nitrogen sources in combination with a hypervalent iodo(III) reagent as oxidant (see scheme; Tos=toluenesulfonyl).