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A Geometric Approach to the Crystallographic Solution of Nonconventional DNA Structures: Helical Superstructures of d(CGATAT)
Author(s) -
Martínez de Ilarduya Iñaki,
De Luchi Daniela,
Subirana Juan A.,
Campos J. Lourdes,
Usón Isabel
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201003647
Subject(s) - set (abstract data type) , crystallography , computer science , dna , topology (electrical circuits) , engineering drawing , chemistry , mathematics , combinatorics , engineering , programming language , biochemistry
Thinking outside the box : A geometrical approach for the molecular‐replacement solution of DNA crystal structures has been applied to solve the superstructures formed by d(CGATAT). Both B‐ and Z‐form duplexes are stacked and form a complex set of intercrossed helical structures of unique topology.