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Acceleration of the Substitution of Silanes with Grignard Reagents by Using either LiCl or YCl 3 /MeLi
Author(s) -
Hirone Naoki,
Sanjiki Hiroaki,
Tanaka Ryoichi,
Hata Takeshi,
Urabe Hirokazu
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201003174
Subject(s) - silanes , reagent , substitution (logic) , acceleration , grignard reagent , chemistry , catalysis , organic chemistry , combinatorial chemistry , computer science , physics , silane , classical mechanics , programming language
Getting up to speed : Both LiCl and the YCl 3 /MeLi catalyst system have an acceleration effect upon the substitution of silanes using Grignard reagents (see scheme). The method provides access to benzyl‐, allyl‐, and arylsilanes in good yields from the starting silanes.