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Chiral Phosphoric Acid Catalyzed Peroxidation of Imines
Author(s) -
Zheng Wenhua,
Wojtas Lukasz,
Antilla Jon C.
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201002972
Subject(s) - phosphoric acid , nucleophile , electrophile , catalysis , chemistry , combinatorial chemistry , organic chemistry , computer science
Something to COO about : The title reaction provides direct access to α‐amino peroxides with high enantioselectivity (see scheme). The phosphoric acid catalyst is thought to activate both the nucleophile and electrophile through hydrogen‐bonding interactions.