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A Versatile Catalyst for Reductive Amination by Transfer Hydrogenation
Author(s) -
Wang Chao,
Pettman Alan,
Bacsa John,
Xiao Jianliang
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201002944
Subject(s) - reductive amination , formic acid , transfer hydrogenation , scope (computer science) , iridium , catalysis , substrate (aquarium) , amination , chemistry , selectivity , combinatorial chemistry , hydrogen , boron , organic chemistry , computer science , ruthenium , oceanography , programming language , geology
An iridium catalyst enables the reductive amination of carbonyl groups with unprecedented substrate scope, selectivity, and activity using formic acid as the hydrogen source (see scheme). The catalyst system provides significant improvement over commonly used boron hydrides.