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A Quantum‐Dot‐Based Molecular Ruler for Multiplexed Optical Analysis
Author(s) -
Morgner Frank,
Geißler Daniel,
Stufler Stefan,
Butlin Nathaniel G.,
Löhmannsröben HansGerd,
Hildebrandt Niko
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201002943
Subject(s) - quantum dot , förster resonance energy transfer , energy transfer , ruler , luminescence , multiplexing , nanotechnology , optoelectronics , computer science , quantum , physics , materials science , optics , engineering physics , fluorescence , telecommunications , quantum mechanics
Nanoshapes and sizes : A time‐resolved multicolor optical analysis of Förster resonance energy transfer (FRET) from a luminescent terbium complex to different semiconductor quantum dots allows the rapid and accurate measurement of the size and shape of different functionalized quantum dots under physiological conditions. This spectroscopic ruler opens the possibility of a simultaneous analysis of different biological processes at sub‐nanomolar concentrations.