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Scanning Imaging of Magnetic Nanoparticles for Quantitative Molecular Imaging
Author(s) -
Yao Li,
Jamison Andrew C.,
Xu Shoujun
Publication year - 2010
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.201002830
Subject(s) - magnetometer , nanoparticle , magnetic nanoparticles , molecular imaging , magnetic field , materials science , magnetization , molecule , nuclear magnetic resonance , nanotechnology , chemistry , physics , microbiology and biotechnology , organic chemistry , quantum mechanics , in vivo , biology
Quantitative molecular imaging : Labeled magnetic nanoparticles serve as molecular probes that bind to specific antibody molecules. The magnetic field of the bound particles is detected using scanning magnetic imaging with an optical atomic magnetometer based on the magnetooptical property of alkali metals. The magnetization, and thus the number of the antibody‐bound magnetic nanoparticles, and the corresponding two‐dimensional spatial information are obtained simultaneously.